Why Do I Go Wet Before My Period?

GNTHM (GermanysNextTopHouseMover)

Phew ... almost done!

The most important things in this last weekend all the way (the court) made it into our new small house. The way was short, but also a "short move" is quite exhausting.

Since "inzeitungeinwickeln" is long, cumbersome box with packing would not have paid in time, we have virtually the entire household goods piecemeal chauffeured from old to new. This advantage of the journey was made almost destroyed ... we think not at all, how many individual parts so flying around in kitchen drawers!

To us (due to bad weather, but quite mushy) Umzugsweg Sun Cabinet as possible urban uniform had our fathers a great idea. Tadaaa: the ultimate genius and today patented, unique work catwalk!

the catwalk for GermanysNextTopHouseMover

form better way to move almost at all. And the part is built to last forever ;-) Maybe we'll save the expensive driveway and just sow grass around the runway around :-))

Otherwise, we are pretty well on target. This was also really just the fact before our wedding essentials, that is, bed, couch, clothes, kitchen utensils and PC to move.

order to make it but a bit homely Tanya has already hung the curtains in the bedroom and living-dining area. So much time has to be!

Attentive viewers of this image have certainly probably our most valuable belongings espied: the Kätzies also have moved into their new home on Saturday.

And after a brief introductory tour of the entire premises (only the two potential children are locked for cats), the two ladies seem to have really good feeling.

our sporadic furnished living room ... incl satisfied puss

The next weeks will be available after the wedding, all about the "comfortable making. Finally, some fully assembled furniture and even a few cabinets are moved.

... We will report :-)

The Best Remedy For Verruca

last work before moving

The weekend looming ;-)

Some things were or are still on our "Nochzuerledigenliste. A few of these things we could tick off in the last few days but (also thanks to some hard-working helpers):

first Laminate and lighting in the work

After the gallery and the bedroom a long time ago by a professional who had been transferred, came early in the week the work on the series. The two children have for our move at the weekend not to be ready, so we have since ran again later! Includes ceiling lamp is the work almost complete. Only the skirting must be installed.

second Lighting:

side of the lamp in the study were still attached to the lights in the bathroom (same lamp as in the study) and the outside lights on the front door.

Especially after the outdoor lighting we had to look pretty long. Somehow We were able to make most from the offer of local furniture stores and DIY stores is not really convincing. Found what we were finally in a lamp store.

And they look out the good bits:

third The house number:

Another indication that at last the river winds down, that our house has finally got a house number is missing! This was a similar severe birth, such as external lights. But here we are looking for a long long time on the web find become!

The house number is a solar light with individual Beschfriftung (color, font, number and text can be selected). To make it google street view not to make too easy, we have airbrushed out the street name but ;-)

4th The bathroom window

floor ceiling windows in the bathroom are so beautiful ... but have a decisive disadvantage: they deliver a truly world-class neighbors panoramic views of EVERYTHING that you all day there is so ;-)

So I needed a visual cover! For the lower windows, we quickly for easy frost glass film stick to the decision. After a little Friemelei this was also appropriate and not at times looks so bad!

For the top two, large window should be something special but her. Again, it was not so easy to find something adequate (because we are soooo demanding ????).

vertical blinds and normal blinds were somehow not as the right one. The race then made two "pleats, pleated blinds or Roman blinds also called ;-). But where to get nice? In Hardware gabs again nothing ordinary ...

problem can be once again the love web. We found a shop that is a huge Auwahl of fabrics and made to measure offered. So fixed was measured, selected and finally installed today! The pattern should match the wallpaper, of course ... So gabs again: FLOWER (what else, if the lady of the house for choice) ;-)) but from looking great and the quality is super!

5th Curtains

Also today, the first preparations were made for the curtains. These will then be attached ... maybe tomorrow We'll see whether we come to it. Finally, still waiting on the wall unit, assembled and installed to be.

Tawnee Stone Accident

vitamin D - this should ALL know about vitamin D !!!!!

importance of vitamin D3 and calcium for
human health (as of 12/09)

Dr. Anna Dorothea Hock • Doctor of Internal Medicine, Cologne

Why is vitamin D intake important?

Vitamin D is important for:
• supporting and connective tissue, extracellular matrix (including bones, joints, muscles, teeth and supporting structures) [6,8,29,30,58,60,91,100]
• Record in the gut and retention of calcium and phosphate in the body
[4,9,10,12,23,26,120,122-124]
• immune system (germ defense, immune regulation, braking of auto-immune processes)
[11.14-19; 22,25,40,50,52,63,64,66,90,97,127]
• Heart and circulatory functions [44,77,78,132]
• Child activity of genes and gene products, formation of [14 to 16.71, 84,101,125]
• signal transduction in cells and influence metabolism [71,84,86,99]
• Hormonal balance (works with other hormones)
[30,52,53,73,21,37,38,54,62, 70,75,85,87,98,104,105,110,115,119]
• Effective against oxidative and reductive stress and thereby obtains the necessary "Redox Balance
[36,57,59,61,95,126]
• Mental functions (life force and joy, alertness, awareness, inner peace,
stress resilience, sleep) [14,39,50,51]

http://www.orthobiovital.de/biogena---produkte-az/biogena-vitamin-d.php


Why does vitamin D something to do with the sun?
Under sunlight made it in [52,96,116]:
• phyto-and zoo-plankton
• Plants as ergocalciferol (vitamin D2) •
animals and humans in the subcutaneous fat cells than cholecalciferol (vitamin D3)

http://www.orthobiovital.de/biogena---produkte-az/biogena-vitamin-d.php

What causes a Vitamin D deficiency?
The conditions of our Western lifestyle and settling of people in
zones of the globe that are further away from the equator, is not enough sun on the skin of the human
[14,52,82,98,101,116-118].
beneficiaries of vitamin D deficiency include: • Clothing

• sun protection factor of 8 from use up
• long working hours in buildings
• dark Ethnicity
• inability without assistance to go outside
• Through enzyme induction, such as alcohol abuse, certain drugs (for epilepsy,
depression, psychosis, transplant rejection) [30,52,96]

http://www .orthobiovital.de / Biogena --- products-az / Biogena-vitamin-d.php

Is vitamin D in sufficient quantities present in food? [47,52,96,116,117]
No for Western European diet and included in the amounts of food are small compared
the amount that can be achieved by a single sun (about 10,000 IU).
vitamin D as a fat-soluble substance is enriched in:
• fatty fish (eg salmon), especially if they live wild (it can contain up to 100 grams
1000 IU vitamin D3)
• cod liver oil (1 tsp 500 IU vitamin D3)
• Fish oils •
certain fungi (eg 100 grams of shiitake, sun-dried, can be about 1600 IU vitamin D2
be included)

http://www.orthobiovital.de/biogena---produkte-az/biogena-vitamin-d.php

How can a vitamin D deficiency be diagnosed?
not make sense is the determination of "activated" 1,25-dihydroxyvitamin [1,25 (OH) 2D3], since its height
nothing about the supply of vitamin D3 says. In contrast, the 25-hydroxyvitamin D3
blood levels [25 (OH) D3] a very reliable measure of the current vitamin D status. 25 (OH) D3
can be easily measured in the blood [14,15,50-52,96,116-118]. It must be remembered however, that a unique
measured value, which is in the desired range, but do not mention year-round supply of vitamin D
, unless it is consistently substituted.
If the level is below 30-40 ng / ml (80-100 nmol / L) are located, for these diverse biological functions
no longer given optimal conditions [14,15,47,50-53,92,96,106,118].
is why it malfunctions and finally to multi-system diseases [89].

http://www.orthobiovital.de/biogena---produkte-az/biogena-vitamin-d.php

Which vitamin D supplements are available?
• ergocalciferol (vitamin D2) (if the content is declared as calciferol, is vitamin D2 included)
• cholecalciferol (vitamin D3)
• From heavy fish oils freed cod liver oil (disadvantage: low cholecalciferol dose and additional
a 10 x higher proportion of vitamin A with the risk of vitamin A overdose)

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Why is increasing the substitution of cholecalciferol (vitamin D3)
take ergocalciferol (D2 Vitam) favors?
Vitamin D2 is biologically weaker than vitamin D3, but shifts of 25 (OH) D3-
mirror provision in the measure with one, so that the biological activity can be assessed worse
[55.116].

http://www.orthobiovital.de/biogena---produkte-az/biogena-vitamin-d.php

How can optimal vitamin D3 levels [25OHD3] of 40-80 ng / be achieved ml
(100-ca. 200 nmol / L)?
Not if the by the World Health Organisation (WHO) designated dose of 500 to 800 IU
(12.5 to 20 mcg) per day are taking.
These doses are for adults and even infants inadequately low.
by recent studies and observations has been found that only doses of 2,000 IU
(50 mcg) to help a powerful immune system, which is also dangerous pathogens such as influenza viruses can fend
[7,14,15,48]. Therefore, there is now in the English speaking
a dose of 2,000 IU (50 mcg) than the highest safe daily dose [52]. It was also about
also found that many people even in this dose not have any desirable
25 (OH) D3 levels reach about 40 ng / ml (100 nmol / L). In these cases, using the
level measurements, the individual needs are identified, [50,51,117]. In practice, this means
: The not-the-counter in drug stores and pharmacies vitamin DPräparate
cover your true need for vitamin D. Their real needs are better met by
abroad-the-counter and mail order available
higher doses of vitamin D supplements. Since
shall, however, the pharmaceutical manufacturer in selling the limits of WHO as alleged
daily requirements based on need, the dose of 2,000 IU (50 mcg) in a tablet than 500%
of the daily requirement declared that unfortunately layman, very wrong to confuse
and can irritate.
Clinical experience shows that for therapeutic purposes, for example, if the immune strengthening
administered, often daily doses of 5000-10000 IU (125 to 250 mcg) are needed to the
25 (OH) D3 levels to a minimum of 40 ng / ml (100 nmol / L) to raise [50-52,117,118].

http://www.orthobiovital.de/biogena---produkte-az/biogena-vitamin-d.php

Why is a combined intake of vitamin D3 and calcium important?
A deficiency in vitamin D, it is inevitable over time also
a lack of calcium. If vitamin D3 levels [25 (OH) D3] below 40 ng / ml (100 nmol / L) decreases, no
adequate calcium in the intestine is longer guaranteed [4,26,42,45,46,93,120]. If the body
decreases the supply of calcium, which not only has serious consequences for the bones because they
then decalcified [45.80], but biological structures, such as proteins or bony supporting tissues
descale as well [2,33,67 ]. Calcium serves as a buffer against protons, acts to counter the chronic
acidity. Calcium helps to form proteins, their secondary structure [67]. The
in the status of vitamin D deficiency, inadequate Calcium binding results in changes of the form
and function of proteins that are manifested clinically only as a function disorders, and later as undetectable
disease and even lead to a vitamin D resistance may [2,33,44,47,50-52].
is also the function of genes and cells in many ways by a lack of calcium
changed to the same extent as in a lack of vitamin D [2,20,24,28,33,65,76,102,124,
128.130].
Thus it can be a lack of vitamin D and calcium from biochemical, molecular and clinical perspective
considered separately. As a result long-term consequence for both
defects the same clinical manifestations [11,13-15,34,35,47,50,52,54,62,69,77,79,80,81,83,107,109,
119,123,128,129,130].

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How can we prove there is a lack of calcium?
Bad, because the calcium in the blood by means of leaching of calcium from the bone is very long in the normal range
is held. A sure sign of a calcium deficiency is an increase
of parathyroid hormone (parathyroid hormone), although this increase is caused by other factors
, also may be absent [12,20,33,43,46,80,92,93,128,129]. How much calcium

should be taken?
Our Western European diet is low in calcium. Often, only 300 mg of elemental calcium per day
recorded, although the daily requirement is given of the healthy with at least 1,000 mg
[1,42-46,68,93,120-124]. Growing children, elderly and ill people need higher doses
. The maximum daily dose is given at 2,400 mg elemental calcium [42-46,121,122].
calcium is to be distributed because of the maximum attainable only recording of the intestines of 600 mg per meal
to 2 to 6 times the single dose [68].

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How long should vitamin D3 and calcium to be taken?
Adapted to health, climate and lifestyle least substitution on sun-free
days. To accompanying adequate dietary intake of calcium or substitution of calcium
should be respected.
already recommended for chronic sufferers, the lifetime duration of treatment in combination with calcium
. The duration of intake contributes to a better overall health with
enhanced well-being, lack of susceptibility to infection and lack of exhaustion
[14,39,50-52,66,127]. The long term goal of such a life-long substitution in addition to the positive
influencing the course of any chronic disease, in particular the prevention of osteoporosis with age
significant curvature of the spine and general muscle weakness
[8,23,26,27,29,43,44,58,80,82,100].

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threatening kidney stones or calcifications in the administration of vitamin D3 and calcium? [32,92,94,106]
If the specified limits are taken into account, NO.
shows the contrary, clinical experience, that people who are as prone to kidney stones, under
vitamin D3 administration have even less stone passage than without calcium and phosphate. This is
because Vitamin D3 causes the biologically meaningful installation (ie chemical bonding) of calcium and phosphate and other calcium
the improved vitamin D-resistant or prevented. For security reasons, but
with a tendency to kidney stones as possible with
calcium citrate can be substituted.

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Who is at increased risk for vitamin D deficiency? [14,15,30,46,50,52,82,91,98,116,117]
• People who are poleward side of the 40th, but especially beyond the 46. Latitude are
Naples is located north of 40th, of Lake Como in the 46th, approximately at the 48th Munich, Berlin
about at the 52st Latitude
• Cities generally in the range of latitudes • due to air pollution
• Sunscreen users (from sun protection factor of 8 upwards)
• Do not open the end of work
• People with long hours indoors
All who are unable to move under its own power into the open
• People with darker skin color
• people with aging skin and premature infants because of lower subcutaneous adipose tissue
• People in detention
• People taking certain medications take (for epilepsy, depression, psychosis,
transplant rejection)
• People who take a lot of alcohol has to be
Who is an increased risk for a lack of calcium and vitamin D
a resulting resistance? [1,23,42-47,56,58,72]
• People with intestinal diseases and / or diarrhea
• People with lactose intolerance or dislike of milk and milk products
• People who take much alcohol addicts

• • hungry and poor people
• People who perform physical extreme performance (sweat contains lots of calcium, eg
Athletes or blast furnace workers)
• Expectant and lactating mothers

http://www.orthobiovital.de/biogena---produkte-az/biogena-vitamin-d.php

What diseases are now a chronic deficiency of vitamin D3 and calcium
brought in context?
• Rheumatoid arthritis and ankylosing spondylitis [14,25,44,52,64,71,83,96]
• Crohn's disease and ulcerative colitis [14,25,44,52,64,71,83,96]
• Multiple sclerosis [14,25,44,52,64,71,83,96]
• chronic infections (upper respiratory tract, urinary tract and abdomen) [15,52,66,97,127]
• premenstrual syndrome, eclampsia, polycystic ovary, endometriosis [88.111-113]
• periodontal disease, tooth loss, caries [6.60]
• rickets, osteoporosis, osteochondritis [10,29,52,80,91,100]
• Diabetes mellitus Type 1 and 2 [53,73,74,103]
• Cardiovascular disease, heart failure, high blood pressure, obesity
[44,69,77,79,81,107,108,130,131]
• scleroderma and psoriasis [12,14,44,52,71]
• colorectal cancer and adenomas, breast cancer, prostate cancer and hypertrophy [3,21,35,37,38,62,70,75,85,87,
98,105,110,115,119]
• Fibromyalgia (Erwachsenenrachitis?) [38,50,52]
• chronic depression and chronic insomnia [39,50,52]
• • fatigue syndrome [39,50,52]
old age [39.50]
• epilepsy [12, 14,44,52,71,83] Additional
own observations (Verdacht!):
• restless legs?
Reason: Lack of calcium affects the excitability of the nerve within the meaning of
hyperexcitability.
• Multiple Chemical Sensitivity (MCS)?
Reason: Already in the early stages of a vitamin D deficiency is a significant disturbance of
observed detoxification. Allergies were used (rightly?) associated with a lack of calcium in
context.

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How can the basis of the symptoms already a shortage of vitamin D3 and suspect
calcium?
There are many symptoms that indicate a lack of calcium and vitamin D [14,15,39,50-52,
96,114,127]. From stage to stage regular, yet add more complaints. In advanced cases, with another
defects [50,51,89]:
initial stage (for detecting and treating reversible full): Not
• tiredness and fatigue and impaired concentration, nervousness •

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• restorative sleep
• cravings for sweets
• General malaise
• Drive faults
• listlessness
• joylessness
middle stage (usually also reversible):
• Frequent infections (upper and lower respiratory tract, urinary tract and abdomen)
• Allergies, First intolerance (pseudo allergies)
• Functional complaints in all organs (from tests normal findings)
• musculoskeletal pain (nor changing places and not continuous)
• Clearer sleep
• drying of the skin and mucous membranes
become chronic stage (reduction by treatment possible, complete recovery doubtful):
• Severe fatigue and weakness, with clear functional loss (job,
daily activities, social contacts)
• Severe intolerance reactions to food and materials of everyday life
• Change the primary personality
• Chronic and all over the body Distributed by pain "neuropathic" character
• ADDED chronic severe disorders such as including rheumatic, autoimmune or inflammatory
degenerative diseases, cancer
• Addition of secondary deficiencies occur by oxidative and reductive stress

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Literature:
first Alekel DL, Matvienko O. Influence of lifestyle choices on calcium homeostasis: smoking, alcohol, and
hormone therapies. In: Calcium in Human Health. Weaver CM, Heaney RP, ed Totowa, New Jersey, Humana Press Inc. 2006:209-225
.
2. Awumey EM, Bukoski RD. Cellular functions and fluxes of calcium. In: Calcium in Human Health. Weaver
CM, Heaney RP, eds. Totowa, New Jersey: Humana Press 2006; 13-37.
3. Bareis P, Bises G, Bischof MG, et al. 25-hydroxyvitamin D metabolism in human colon cancer cells during
tumor progression. Biochem Biophys Res Commun 2001;285:1012-1017.
4. Barger-Lux MJ, Heany RP, Lanspa SJ, et al. An investigation of sources of variation in calcium absorption
efficiency. J Clin Endocrinol Metab 1995;80:406-411.
5. Barsoum GH, Hendrickse C, Winslet MC, et al. Reduction of mucosal crypt cell proliferation in patients
with colorectal adenomatous polyps by dietary calcium supplementation. Br J Surg 1992;79:581-583.
6. Berdahl A, Bailleul-Forestier I, Davideau JL, et al. Dento-alveolar bone complex and vitamin D. In: Vitamin
D. Feldman D, Pike JW, Glorieux FH, ed. New York, Elsevier Press Inc. 2005:599-607.
7. Bischoff-Ferrari HA. Optimal serum 25-hydroxyvitamin D levels for multiple health outcomes. Adv Exp
Med Biol 2008; 624:55-71.
8. Boland RL. Vitamin D and muscle. In: Vitamin D. Feldman D, eds. Amsterdam: Elsevier Academic Press
2005; 883-897.
9. Boonen S, Lips P, Bouillon R, et al. Need for additional calcium to reduce the risk of hip fracture with vitamin
D supplementation: evidence from a comparative meta-analysis of randomized controlled trials. J Clin
Endocrin & Metabol 2007; 92:1415-1423.
10. Boyan BD, Schwartz Z. Cartilage and vitamin D: Genomic and nongenomic regulation by 1,25(OH)2D3
and 24,25 (OH)2D3. In: Vitamin D. Feldman D, eds. Amsterdam: Elsevier Academic Press 2005; 575-597.
11. Brannon PM, Yetley EA, Bailey RL, et al. Overview of the conference “Vitamin D and Health in the 21st
century: an Update”. Am J Clin Nutr 2008; 88(2):483S-490S.
12. Bringhurst FR, Demay MB, Krane S, et al. Bone and mineral metabolism in health and disease. In:
Harrison’s Principles Of Internal Medicine. Kasper DL, Fauci AS, Longo DL et al. eds. New York, McGraw-
Hill Companies, Inc. 2005:2238-2249.
13. Bucher HC, Cook RJ, Guyatt GH, et al. Effects of dietary calcium supplementation on blood pressure: a
meta-analysis of randomized controlled trials. J Am Med Assoc 1996;275:1016-1022.
14. Cannell JJ, Hollis BW, Zasloff M, et al. Diagnosis and treatment of vitamin D deficiency. Expert Opin
Pharmacother 2008; 9(1):107-118.
15. Cannell JJ, Hollis BW. Use of vitamin D in clinical practice. Altern Med Rev 2008; 13(1): 6-20.
16. Carlberg C, Dunlop TW, Frank C, et al. Molecular basis of the diversity of vitamin D target genes. In:
Vitamin D. Feldman D, eds. Amsterdam: Elsevier Academic Press 2005; 313-325.
17. Chang JM, Kuo MC, Kuo HAT, et al. 1-alpha,25-dihydroxyvitamin D3 regulates inducible nitric oxide synthase
messenger RNA expression and nitric oxide release in macrophage like RAW 264.7 cells. J Lab Clin
Med 2004; 143:14-22.
18. Chatterjee M. Vitamin D and genomic stability. Mutation Research 2001; 475:69-88.
19. Cohen MS, Mesler DE, Snipes RG, et al. 1,25-dihydroxyvitamin D3 activates secretion of hydrogen peroxide
by human monocytes. J Immunol 1986; 136:1049-1053.
20. Coleman DT, Fitzpatrick LA, Bilezikian JP. Biochemical mechanisms of parathyroid hormone activation. In:
The Parathyroids. Bilezikian JP, ed. New York: Raven Press 1994; 239-258.
21. Cross HS. Vitamin D and colon cancer. In: Vitamin D. Feldman D, Pike JW, Glorieux FH, ed. New York,
Elsevier Press Inc. 2005:1709-1725.
22. D’Ambrosio D, Cippitelli M, Cocciolo MG, et al. Inhibition of IL-12 production by 1,25-dihydroxyvitamin
D3. Involvement of NF-kappa B downregulation in transcriptional repression of the p40 gene. J Clin
Invest 1998; 101:252-262.
23. Dawson-Hughes B. Calcium throughout the life cycle: the later years. In: Calcium in Human Health.
Weaver CM, Heaney RP, ed. Totowa, New Jersey, Humana Press Inc. 2006:371-385.
24. Degasperi GR, Velho JA, Zecchin KG, et al. Role of mitochondria in the immune response to cancer: a
central role for Ca2+. J Bioenerg Biomembr 2006;38:1-10.
25. DeLuca HF, Cantorna MT. Vitamin D: Its role and uses in immunology. FASEB 2001; 15:2579-2585.
http://www.orthobiovital.de/biogena---produkte-a-z/biogena-vitamin-d.php 8
26. Devine A, Wilson SG, Dick IM, et al. Effects of vitamin D metabolites on intestinal calcium absorption and
bone turnover in elderly women. Am J Clin Nutr 2002;75(2):283-288.
27. Disthabanchong S, Radinahamed P, Stitchantrakul W, et al. Chronic metabolic acidosis alters osteoblast
differentiation from human mesenchymal stem cells. Kidney Int 2007;71:201-209.
28. Dolmetsch RE, Lewis RS, Goodnow CC, et al. Differential activation of transcription factors induced by
Ca2+response amplitudes and duration. Nature 1997;386:855-858.
29. Eastell R, Riggs BL. Vitamin D and osteoporosis. In: Vitamin D. Feldman D, Pike JW, Glorieux FH, ed.
New York, Elsevier Press Inc. 2005:1101-1120.
30. Epstein S, Schneider AE. Drug and hormone effects on vitamin D metabolism. In: Vitamin D. Feldman D,
Pike JW, Glorieux FH, ed. New York, Elsevier Press Inc. 2005:1253-1291.
31. Farach-Carson MC, Bergh JJ. Effects of 1,25-dihydroxyvitamin D3 on voltage-sensitive calcium channels
in the vitamin D endocrine System. In: Vitamin D. Feldman D, eds. Amsterdam, Elsevier Academic Press
2005; 751-60.
32. Favus MJ, Coe FL. Idiopathic hypercalciuria and nephrolithiasis. In: Vitamin D. Feldman D, Pike JW,
Glorieux FH, ed. New York, Elsevier Press Inc. 2005:1339-1354.
33. Fleet JC. Molecular regulation of calcium metabolism. In: Calcium in Human Health. Weaver CM, Heaney
RP, ed. Totowa, New Jersey, Humana Press Inc. 2006:163-189.
34. Foss YJ. Vitamin D deficiency is the cause of common obesity. Med Hypotheses 2009; 72:314-321.
35. Gallus S, Bravi F, Talamini R et al. Milk, dairy products and cancer risk (Italy). Cancer Causes Contr
2006;17:429-437.
36. Garcion E, Sindji L, Leblondel G, et al. 1,25-dihydroxyvitamin D3 regulates the synthesis of gamma-glutamyl
transpeptidase and glutathione levels in rat primary astrocytes. J Neurochem 1999; 73:859-866.
37. Garland F, Garland C, Gorham E, et al. Geographic variation in breast cancer mortality in the United
States: a hypothesis involving exposure to solar radiation. Prev Med 1990;19:614-622.
38. Giovannucci E, Platz E. Epidemiology of cancer risk. Vitamin D and calcium. In: Vitamin D. Feldman D,
Pike JW, Glorieux FH, ed. New York, Elsevier Press Inc. 2005:1617-1634.
39. Glerup H, Eriksen EF. Muscles and falls. In: Vitamin D. Feldman D, eds. Amsterdam: Elsevier Academic
Press 2005; 1805-1820.
40. Griffin MD, Lutz W, Phan VA, et al. Dendritic cell modulation by 1 ,25- dihydroxyvitamin D3 and its
analogs: A vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro
and in vivo. Proc Natl Sci U S A 2001; 98(12):6800-6805.
41. Hatchcock JN, Shao A, Vieth R, et al. Risk assessment for vitamin D. Am J Clin Nutr 2007; 85(1):6-18.
42. Heaney RP, Weaver CM. Requirements for what endpoint? In: Calcium in Human Health. Weaver CM,
Heaney RP, ed. Totowa, New Jersey, Humana Press Inc. 2006:97-104.
43. Heaney RP. Bone as the calcium nutrient reserve. In: Calcium in Human Health. Weaver CM, Heaney RP,
ed. Totowa, New Jersey, Humana Press Inc. 2006:7-12.
44. Heaney RP. Calcium in systemic human health. In: Calcium in Human Health. Weaver CM, Heaney RP,
eds. Totowa, New Jersey: Humana Press 2006; 313-317.
45. Heaney RP. Normalizing calcium intake: projected population effects for body weight. J Nutr
2003;133:268S-270S.
46. Heaney RP. The calcium economy. In: Calcium in Human Health. Weaver CM, Heaney RP, ed. Totowa,
New Jersey, Humana Press Inc. 2006:145-162.
47. Heaney RP. Vitamin D and calcium interactions: functional outcomes. Am J Clin Nutr 2008; 88(2):541S-544S.
48. Heaney RP. Vitamin D: criteria for safety and efficacy. Nutr Rev 2008; 66(10):S178-S181.
49. Hewison M, Adams JS. Extra-renal 1-alpha- hydroxylase activity and human disease. In: Vitamin D.
Feldman D, eds. Amsterdam: Elsevier Academic Press 2005; 1379-1400.
50. Höck AD. Divalent cations, hormones, psyche and soma: Four case reports. J Chronic Fatigue Syndr
2000; 6(3/4):117-131
51. Höck AD. Fatigue and 25-hydroxyvitamin D levels. J Chronic Fatigue Syndr 1997; 3:117-127.
52. Holick FM. Vitamin D. N Engl J Med 2007; 357:266-281.
53. Holick MF. Diabetes and the vitamin D connection. Curr Diab Rep 2008; 8(5):393-398.
54. Holt PR. Calcium, Vitamin D, and cancer. In: Calcium in Human Health. Weaver CM, Heaney RP, ed.
Totowa, New Jersey, Humana Press Inc. 2006:387-400.
9 http://www.orthobiovital.de/biogena---produkte-a-z/biogena-vitamin-d.php
55. Houghton LA, Vieth R. The case against ergocalciferol (vitamin D2) as a vitamin supplement. Am J Clin
Nutr 2006; 84(4):694-697.
56. Kalkwarf HJ. Calcium in pregnancy and lactation. In: Calcium in Human Health. Weaver CM, Heaney RP,
ed. Totowa, New Jersey, Humana Press Inc. 2006:297-309.
57. Karasawa M, Hosoi J, Hashiba H, et al. Regulation of metallothionein gene expression by 1?,25-dihydroxyvitamin
D3 in cultured cells and in mice. Proc Natl Acad Sci USA 1987; 84:8810-8813.
58. Klesges RC, Ward KD, Shelton ML, et al. Changes in bone mineral content in male athletes. JAMA
1996;276:226-230.
59. Koren R, Ravid A. Vitamin D and the cellular response to oxidative stress. In: Vitamin D. Feldman D, eds.
Amsterdam: Elsevier Academic Press, Inc. 2005; 761-770.
60. Krall EA: Calcium and oral health. In: Calcium in Human Health. Weaver CM, Heaney RP, ed. Totowa,
New Jersey, Humana Press Inc. 2006:319-325.
61. Kröncke KD, Klotz LO, Suschek CV, et al. Comparing nitrosative versus oxidative stress toward zinc finger-
dependent transcription. Unique role for NO. J Biol Chem 2002; 277:13294-13301.
62. Lamprecht SA, Lipkin M. Chemoprevention of colon cancer by calcium, vitamin D and folate: Molecular
mechanisms. Nat Rev Cancer 2003;3:601-614.
63. Lefebvre d’Hellencourt C, Montero-Menei CN, Bernard R, et al. Vitamin D inhibits proinflammatory
cytokines and nitric oxide production in the EOC13 microglial cell line. J Neurosci Res 2003; 71:575-582.
64. Lemire J. Vitamin D3: Autoimmunity and immunosuppression. In: Vitamin D. Feldman D, eds.
Amsterdam: Elsevier Academic Press 2005; 1753-1756.
65. Lewis RS. Calcium oscillations in T-cells: mechanisms and consequences for gene expression. Biochem Soc
Trans 2003; 31:925-929.
66. Liu PT, Stenger S, Li H, et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial
response. Science 2006; 311:1770-1773.
67. Löffler G, Petrides PE, Heinrich PC, eds. Biochemie und Pathobiochemie. Heidelberg: Springer Verlag 2007.
68. Looker AC. Dietary Calcium: Recommendations and intakes around the world. In: Calcium in Human
Health. Weaver CM, Heaney RP, ed. Totowa, New Jersey, Humana Press Inc. 2006:105-127.
69. Loos RJ, Rankinen T, Leon AS, et al. Calcium intake is associated with adiposity in black and white men
and white women of the HERITAGE family study. J Nutr 2004;134(7):1772-1778.
70. Lou YR, Qiao S, Talonpoika R, et al. The role of vitamin D3 metabolism in prostate cancer. J Steroid
Biochem Mol Biol 2004;92:317-325.
71. Lou YR, Tuohimaa P. Is Calcidiol an active hormone? In: New Topics in Vitamin D Research. Stolzt VD,
ed. New York: Nova Science Publishers 2006: 1-28.
72. Lovell G. Vitamin D status of females in an elite gymnastic program. Clin J Sport Med 2008¸18(2):159-161.
73. Maestro B, Campion J, Davila N, Calle C. Stimulation by 1,25-dihydroxyvitamin D3 of insulin receptor
expression and insulin responsiveness for glucose transport in U-937 human promonocytic cells. Endocr J
2000;47:383-391.
74. Maestro B, Davila N, Carranza MC, et al. Identification of a vitamin D response element in the human
insulin receptor gene promoter. J Steroid Biochem Mol Biol 2003;84:223-230.
75. Mathiasen IS, Lademann U, Jäättelä M. Apoptosis induced by vitamin D compounds in breast cancer cells
is inhibited by Bcl-2 but does not involve known caspases or p53. Cancer Res 1999; 59:4848-4856.
76. Mattson MP. Free radicals, calcium, and the synaptic plasticity-cell death continuum; emerging roles of
the transcription factor NF-kB. Int Rev Neurobiol 1998; 42:103-168.
77. McCarron DA. Dietary calcium and lower blood pressure: we can all benefit. JAMA 1996;275:1128-1129.
78. McCarron DA. Hypertension and cardiovascular disease. In: Calcium in Human Health. Weaver CM,
Heaney RP, ed. Totowa, New Jersey, Humana Press Inc. 2006:421-429.
79. McCarty MF, Thomas CA. PTH excess may promote weight gain by impeding catecholamine-induced
lipolysis-implications for the impact of calcium, vitamin D, and alcohol on body weight. Med Hypotheses
2003;61:535-542.
80. McKane WR, Khosla S, Egan KS, et al. Role of calcium intake in modulating age-related increases in
parathyroid function and bone resorption. J Clin Endocrinol Metab 1996;81:1699-1703.
81. Melanson EL, Sharp TA, Schneider J, et al. Relation between calcium intake and fat oxydation in adult
humans. Int J Obes Relat Metab Disord 2003;27:196-203.
82. Meunier PJ, Chapuy MC. Vitamin D insufficiency in adults and the elderly. In: Vitamin D. Feldman D, Pike
JW, Glorieux FH, ed. New York, Elsevier Press Inc. 2005:1085-1100.
http://www.orthobiovital.de/biogena---produkte-a-z/biogena-vitamin-d.php 10
83. Missiaen L, Robberecht W, Van Den Bosch L, et al. Abnormal Ca2+ homeostasis and disease. Cell
Calcium 2000;28:1-21.
84. Nagpal S, Na S, Rathnachalam R. Noncalcemic actions of vitamin D receptor ligands. Endocr Rev 2005;
26:662-687.
85. Newmark H. Vitamin D adequacy: a possible relationship to breast cancer. In Diet and Breast Cancer.
Plenum, New York: 1994:109-114.
86. Norman AW. 1,25(OH)2-vitamin D3 mediated rapid and genomic responses are dependent upon critical
structure-function relationships for both the ligand and the receptor(s). In: Vitamin D. Feldman D, eds.
Amsterdam: Elsevier Academic Press 2005; 381-407.
87. O’Kelly J, Morosetti R, Koeffler HP. Vitamin D and hematological malignancy. In: Vitamin D. Feldman D,
eds. Amsterdam: Elsevier Academic Press 2005; 1727-1740.
88. Ozono K, Nakajima S, Michigami T. Vitamin D and reproductive organs. In: Vitamin D. Feldman D, Pike
JW, Glorieux FH, ed. New York, Elsevier Press Inc. 2005:851-861.
89. Pall ML: Common etiology of posttraumatic stress disorder, fibromyalgia, chronic fatigue syndrome and
multiple chemical sensitivity via elevated nitric oxide/peroxinitrite. Med Hypotheses 2001; 57:139-145.
90. Penna G, Amuchastegui S, Giarratana N, et al. 1,25-dihydroxyvitamin D3 selectively modulates tolerogenic
properties in myeloid but not plasmacytoid dendritic cells. J Immunol 2007; 178:145-153.
91. Pettifor JM. Vitamin D deficiency and nutritional rickets in children. In: Vitamin D. Feldman D, Pike JW,
Glorieux FH, ed. New York, Elsevier Press Inc. 2005:1065-1083.
92. Potts JT. Diseases of the parathyroid gland and other hyper- and hypocalcemic disorders. In: Harrison’s
Principles Of Internal Medicine. Kasper DL, Fauci AS, Longo DL et al. eds. New York, McGraw-Hill
Companies, Inc. 2005:2245-2268.
93. Roughead Z K. Influence of total diet on calcium homeostasis. In: Calcium in Human Health. Weaver
CM, Heaney RP, ed. Totowa, New Jersey, Humana Press Inc. 2006:191-207.
94. Rubin MR, Thys-Jacobs S, Chan FKW, et al. Hypercalcemia due to vitamin D toxicity. In: Feldman D, Pike
JW, Glorieux FH, ed. New York, Elsevier Press Inc. 2005:1355-1377.
95. Sardar S, Chakrabarty A, Chatterjee M. Comparative effectiveness of vitamin D3 and vitamin E on peroxidation
of lipids and enzymes of the hepatic antioxidant system in Sprague-Dawley rats. Int J Vit Nutr Res
1996; 66:39-45.
96. Saul AW. Vitamin D: deficiency, diversity and dosage (J Orthomolec Med 2003;18(3,4):194-204.
97. Schauber J, Dorschner RA, Coda AB, et al. Injury enhances TLR2 function and antimicrobial peptide
expression through a vitamin D-dependent mechanism. J Clin Invest 2007; 117:803-811.
98. Schwartz GG, Hanchette CL. UV, latitude, and spatial trends in prostate cancer mortality: All sunlight is
not the same (United States). Cancer Causes Contr 2006;17:1091-1101.
99. Sitrin MD, Bissonnette M, Bolt MJ, et al. Rapid effects of 1,25 (OH)2 vitamin D3 on signal transduction
systems in colonic cells. Steroids 1999;64(1-2):137-142.
100. Stern PH. Bone. In: Vitamin D. Feldman D, Pike JW, Glorieux FH, ed. New York, Elsevier Press Inc.
2005:565-573.
101. Stumpf WE, Privette TH. Light, vitamin D and psychiatry. Role of 1,25 dihydroxyvitamin D3 (soltriol) in
etiology and therapy of seasonal affective disorder and other mental processes. Psychopharmacology
1989; 97:285-294.
102. Sun X, Zemel MB. Dietary calcium regulates ROS production in aP2-agouti transgenic mice on highfat/
high-sucrose diets. Int J Obes 2006;30:1341-1346.
103. Suzuki A, Kotake M, Ono Y, et al. Hypovitaminosis D in type 2 diabetes mellitus: association with
microvascular complications and type of treatment. Endocrine J 2006;53:503-510.
104. Tangpricha V, Flanagan JN, Whitlatch LW, et al. 25-hydroxy-vitamin D-1alpha-hydroxylase in normal and
malignant colon tissue. Lancet 2001;357:1673-1674.
105. Tangrea J, Helzlsouer K, Pietinen P, et al. Serum levels of vitamin D metabolites and the subsequent risk
of colon and rectal cancer in Finnish men. Cancer Causes Control 1997;8:615-625.
106. Tebben P, Kumar R. Vitamin D and kidney. In: Vitamin D. Feldman D, Pike JW, Glorieux FH, ed. New
York, Elsevier Press Inc. 2005:515-536.
107. Teegarden D. Dietary calcium and obesity. In: Calcium in Human Health. Weaver CM, Heaney RP, ed.
Totowa, New Jersey, Humana Press Inc. 2006:327-339.
108. Teegarden D. Dietary calcium and the metabolic syndrome. In: Calcium in Human Health. Weaver CM,
Heaney RP, ed. Totowa, New Jersey, Humana Press Inc. 2006:401-409.
11 http://www.orthobiovital.de/biogena---produkte-a-z/biogena-vitamin-d.php
109. ThacherTD, Fischer PR, Pettifor JM, et al. A comparison of calcium, vitamin D, or both for nutritional rickets
in Nigerian children. N Engl J Med 1999; 341(8):563-604.
110. Thomas MG, Tebbutt S, Williamson RC. Vitamin D and its metabolites inhibit cell proliferation in human
rectal mucosa and a colon cancer cell line. Gut 1992;33:1660-1663.
111. Thys-Jacobs S, Donovan D, Papadopoulos A, Sarrel P, Bilezikian JP. Vitamin D and calcium dysregulation
in the polycystic ovarian syndrome. Steroids 1999;64:430-435.
112. Thys-Jacobs S. Polycystic ovary syndrome and reproduction. In: Calcium in Human Health. Weaver CM,
Heaney RP, ed. Totowa, New Jersey, Humana Press Inc. 2006:341-355.
113. Thys-Jacobs S. Premenstrual syndrome. In: Calcium in Human Health. Weaver CM, Heaney RP, ed.
Totowa, New Jersey, Humana Press Inc. 2006:357-369.
114. Turner MK, Hooten WM, Schmidt JE, et al. Prevalence and clinical correlates of vitamin D inadequacy
among patients with chronic pain. Pain Med 2008; 9(8):979-984.
115. Van Leeuwen JPTM, Pols HAP. Vitamin D: Cancer and differentiation. In: Vitamin D. Feldman D, eds.
Amsterdam: Elsevier Academic Press 2005; 1571-1597.
116. Vieth R. The pharmacology of vitamin D, including fortification strategies. In: Vitamin D. Feldman D, eds.
Amsterdam: Elsevier Academic Press 2005; 995-1015.
117. Vieth R. Vitamin D toxicity, policy, and science. J Bone Miner Res 2007; 22(2):V64-V68
118. Vieth R. What is the optimal vitamin D status for health? Prog Biophys Mol Biol 2006; 92(1):26-32.
119. Wargovich MJ, Isbell G, Shabot M, et al. Calcium supplementation decreases rectal epithelial cell proliferation
in subjects with sporadic adenoma. Gastroenterology 1992;103:92-97.
120. Wasserman RH. Vitamin D and the intestinal absorption of calcium: A View and Overview. In: Vitamin D.
Feldman D, Pike JW, Glorieux FH, ed. New York, Elsevier Press Inc. 2005:411-428.
121. Wastney ME, Zhao Y, Weaver CM. Calcium consumption, requirements, and bioavailability. In: Calcium in
Human Health. Weaver CM, Heaney RP, ed. Totowa, New Jersey, Humana Press Inc. 2006: 83-93.
122. Weaver CM, Heaney RP. Food sources, supplements, and bioavailability. In: Calcium in Human Health.
Weaver CM, Heaney RP, ed. Totowa, New Jersey, Humana Press Inc. 2006:129-142.
123. Weaver CM, Heaney RP. Introduction. In: Calcium in Human Health. Weaver CM, Heaney RP, ed.
Totowa, New Jersey, Humana Press Inc. 2006:1-3.
124. Weaver CM. Clinical approaches for studying calcium metabolism and its relationship to disease. In:
Calcium in Human Health. Weaver CM, Heaney RP, ed. Totowa, New Jersey, Humana Press Inc. 2006:65-81.
125. Whitfield GK, Jurutka PW, Haussler CA. Nuclear vitamin D receptor: structure-function, molecular control
of gene transcription, and novel bioactions. In: Vitamin D. Feldman D, eds. Amsterdam: Elsevier
Academic Press 2005; 219-261.
126. Wiseman H. Vitamin D is a membrane antioxidant. Ability to inhibit iron-dependent lipid peroxydation in
liposomes compared to cholesterol, ergosterol and tamoxifen and relevance to anticancer action. FEBS
Lett 1993; 326:285-288.
127. Yamshchikov AV, Desai NS, Blumberg HM, et al. Vitamin D for treatment and prevention of infectious
diseases: a systematic review of randomized controlled trials. Endocr Pract 2009; 15(5):438-449.
128. Yokoyama K, Kagami S, Ohkido I. et al. The negative Ca(2+) balance is involved in the stimulation of
PTH secretion . Nephron 2002;92:86-90.
129. Yokoyama K, Yoshida H, Kato J, et al. The low-calcium concentration of dialysate induced markedly an
increase of serum parathyroid hormone in a continuous ambulatory peritoneal dialysis patient. Kidn Int
2007;71:594.
130. Zemel MB, Shi H, Greer B, et al. Regulation of adiposity by dietary calcium. FASEB J 2000;14:1132-1138.
131. Zemel MB. Role of calcium and dairy products in energy partitioning and weight management. Am J Clin
Nutr 2004;79(5):907S-912S.
132. Zittermann A, Schulze Schleithoff S, Tenderich G, et al. Low vitamin D status: a contributing factor in the
pathogenesis of congestive heart failure. J Am Coll Cardiol 2003; 41:105-12.
Dr. med. Anna Dorothea Höck
Interessenkonflikte: No
Cologne, 28.12.2009

Model-promostions.com

laminate, kitchen, bathroom, wardrobe ... and some other mail from Viebrock!

Phew! Those were turbulent days ... device that is technically quite what was going on in our little hut!

But as usual, all first things first:

Thursday was laid in our bedroom and in the gallery in the laminate floor. As our gallery by the inclined doors but looks pretty good ;-), but this is a nightmare for any laminate lay amateur. Therefore, we decided ranzulassen the professional. And if that is already there, "could" move the bedroom with this same. The Professional

confirmed in the evening then even our fears. Seis really difficult to cut out all the angles and have been suitably use. Therefore, we were ultimately very happy that we had not tried it ... probably would have ended in wild accusations and insults ;-))

But the result is impressive. We are happy in any case, because the laminate is perfectly fit for the selected wallpaper!

The bedroom ...

and the gallery, including storage.

We went on Friday! Around 08:00 clock in the morning time is 2 + 4 trucks moved amazingly slept Craftsmen in order to assemble bathroom furniture and kitchen.

We had the day free and was taken to build step by step experience. Even at the end of the day we were very satisfied, both with the craftsmen as well as with our choice of kitchen and bathroom furniture.

The kitchen

The bathroom furniture:

The toilet:

The wooden mirror has finally taken its place in our toilet ... now our kitschy art space is finite almost completely :-)

The Wardrobe:

The fight was pure. Many, many hours later and thanks 3 men and a woman he was then ... he looks good but from the barrel! And we should place thanks the drawers have plenty of ... But can women have ever enough space for clothes?? I venture to doubt the times ;-)

left the Ladies side, "right is" Mr Page "

And here's the rest of PAXfest ... en Haufe Babbie!

As if this were not enough to have been the highlights, there was a highlight of a very special way on top!

Who gets passed the House receives from Viebrock a nifty booklet with bonuses. And depending on how "good" one is, one must choose a premium. The range of the premium ranges from trips to the shopping vouchers.

We were very well behaved and were delighted at the weekend a very special Viebrock delivery (usually just send the bills so ;-))

Tadaaa: our new toy:

A beautiful gift collection, as we find. Only one downside to the good piece ... it's too big for the glass stage of the newly purchased apartment wall! This was unfortunately designed just for our small 82cm LCD ... but we will think of something there :-)

Soo .. You see, you were eventful days ... and the draw is fast approaching!

Now it's up to us! On the to-do list still stand: delete work Timmer and utility room, Laminate lay, install curtains, hang the lights and build the last living wall. Means that there remains much to do ...

Set Up Wifi Using 3 Donle

before it on Friday with kitchen, laminate flooring and bathroom furniture again really goes around in our cabin, we have taken a few pictures.

Let's start with the still unfurnished, but freshly papered bathroom :

flowers everywhere. I think you can quite clearly see which of us two here "enforced" in the wallpaper selection has ;-) The rest of the bathroom and the ceiling we have papered with painter fleece the company Marburg (patent web). In the last picture you can see the after-market, smaller radiators. Now at last the door opens without problems (see in the picture but from closer than it really is).

Our bedroom received a dashing stripe wallpaper. We are very excited to see how this looks tomorrow together with the laminate.

And here again our corridor. The ceiling light has finally taken its place:

yet the whole thing seems a bit dull ... will change but with the laminate tomorrow hopefully :-)

laminate is also a good point: this is namely also ready to be processed on the next day!

We chose to laminate the company Elesgo. It sounds wonderful on the wellness floor with real oak Structure river and has an impact sound attenuation and is coated anti-static. So finally, no more beatings ;-)

As our gallery due to the very doors installed diagonally nooks and crannies, we have spontaneously decided to have embarrassed the floor in the bedroom and in the gallery by a professional. The rest is up to us then!

Enough hung out on the first floor: here we go first down the stairs ... where you can admire the wall finally mittlerweie lights:

Last Stop: NO .....

.... that is not our living room!! ;-)

time: Tadaa! Our WC!

This wonderful wallpaper we just could not help but buy a chandelier! can

here you can see very well how difficult: The matching wood mirror is already ordered :-)

And here the wallpaper close-up it was right to put the wallpaper on the wall :-)

Soo .. that's it for today. But much remains to be done: in the living room is waiting for our living wall to build on to. On Saturday, our friend from the PAX series ... We are excited to see how we will cope with the construction!

We also are eagerly awaiting our kitchen and bathroom furniture ... Therefore, there will certainly be back soon many new pictures!